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Immunological dysfunction

Description

Immune system is the body's defense mechanism against foreign organisms or substances and deviant native cells. It includes the humoral immune response and the cell-mediated response and consists of a complex of interrelated cellular, molecular, and genetic components. Diseases of the immune system are disorders caused by abnormal or absent immunologic mechanisms, whether humoral, cell-mediated, or both. (Description adapted from https://www.ncbi.nlm.nih.gov/mesh/68007154 and https://www.ncbi.nlm.nih.gov/mesh/68007107)

Research projects (17)
Research types (10)
Research networks (3)
Working groups (9)
People (66)
Publications (40)
Event items (40)

Research projects

Analysing Antibody Responses against EBV-derived Antigens in ME/CFS
Project status:
Completed
Country:
Poland, UK, Germany
Principal investigator:
Carmen Scheibenbogen, Nuno Sepúlveda
Organisations:
Charité – University Medicine Berlin, Warsaw University of Technology
Research period:
2020-10-01
to not available
Research types:
Basic research
Research areas:
Infections, Immunological dysfunction
Association between serum antibodies and exercise intolerance and muscular/neuronal fatigue in ME/CFS
Project status:
Ongoing
Country:
Latvia
Principal investigator:
Bhupesh K. Prusty
Organisations:
Riga Stradins University
Research period:
Not available
Research types:
Basic research
Research areas:
Infections, Immunological dysfunction, Nutritional and metabolic system disorder
Autoantibody-induced Transcriptome and Proteome as Biomarkers
Project status:
Ongoing
Country:
Germany
Principal investigator:
Gabriela Riemekasten
Organisations:
University Clinic Schleswig-Holstein - Luebeck (UKSH)
Research period:
2022-08-01
to 2025-07-31
Research types:
Basic research
Research areas:
Immunological dysfunction
Autoimmunity Risk Variants in the PTPN22 and CTLA4 Genes are Associated with Infectious Onset of ME/CFS
Project status:
Completed
Country:
Germany
Principal investigator:
Sophie Steiner
Organisations:
Charité – University Medicine Berlin
Research period:
Not available
Research types:
Basic research
Research areas:
Immunological dysfunction, Genetic risk factors, General
Biosamples, GPCR-Autoantibodies, Data Management and Bioinformatics
Project status:
Ongoing
Country:
Germany
Principal investigator:
Uta Behrends
Organisations:
University Hospital rechts der Isar (MRI TUM), Technical University of Munich (TUM)
Research period:
2022-08-01
to 2025-07-31
Research types:
Basic research
Research areas:
Immunological dysfunction, General
Chronic Fatigue Syndrome and Immunedeficiencies
Project status:
Completed
Country:
Austria
Principal investigator:
Eva Untersmayer
Organisations:
Medical University of Vienna
Research period:
2019-03-01
to not available
Research types:
Basic research
Research areas:
Infections, Immunological dysfunction
Development of Diagnostic Tests to Detect Autoantibodies in CFS
Project status:
Ongoing
Country:
Germany
Principal investigator:
Carmen Scheibenbogen
Organisations:
Charité – University Medicine Berlin
Research period:
Not available
Research types:
Basic research
Research areas:
Immunological dysfunction
EBV, SARS-CoV-2, HSV Mimicry Epitopes and Autoantibodies
Project status:
Ongoing
Country:
Germany
Principal investigator:
Franziska Sotzny
Organisations:
Charité – University Medicine Berlin
Research period:
2022-08-01
to 2025-07-31
Research types:
Basic research
Research areas:
Infections, Immunological dysfunction, General
Establishing Immunological Assays for the Diagnostics of ME/CFS
Project status:
Ongoing
Country:
Germany
Principal investigator:
Annick Fehrer
Organisations:
Charité – University Medicine Berlin
Research period:
Not available
Research types:
Basic research
Research areas:
Immunological dysfunction
Immune Aberrations in Post-Infectious ME/CFS
Project status:
Ongoing
Country:
Germany
Principal investigator:
Anna Aschenbrenner
Organisations:
German Center for Neurodegenerative Diseases (DZNE)
Research period:
2022-08-01
to 2025-07-31
Research types:
Basic research
Research areas:
Immunological dysfunction
Immunoadsorption in Patients With Chronic Fatigue Syndrome Including Patients With Post-COVID-19 CFS (IA-PACS-CFS)
Project status:
Ongoing
Country:
Germany
Principal investigator:
Harald Pruess
Organisations:
Charité – University Medicine Berlin, German Center for Neurodegenerative Diseases (DZNE)
Research period:
2023-10-01
to 2025-02-28
Research types:
Clinical research
Research areas:
Immunological dysfunction
Immunoadsorption vs Sham Treatment in Post-COVID-19 Patients With Chronic Fatigue Syndrome (EXTINCT post COVID)
Project status:
Ongoing
Country:
Germany
Principal investigator:
Vega Goedecke
Organisations:
Hannover Medical School (MHH)
Research period:
2023-07-01
to 2025-06-30
Research types:
Clinical research
Research areas:
Immunological dysfunction
Methylprednisolone in Patients With Cognitive Deficits in Post-COVID-19 Syndrome (PCS) (PoCoVIT)
Project status:
Ongoing
Country:
Germany
Principal investigator:
Christiana Franke
Organisations:
Charité – University Medicine Berlin
Research period:
2023-10-01
to 2025-03-31
Research types:
Clinical research
Research areas:
Immunological dysfunction, Nervous system disorder
Mitochondrial Dysfunction and Metabolic Changes
Project status:
Ongoing
Country:
Latvia
Principal investigator:
Bhupesh K. Prusty
Organisations:
Riga Stradins University
Research period:
2022-08-01
to 2025-07-31
Research types:
Basic research
Research areas:
Immunological dysfunction, Nutritional and metabolic system disorder
Observational Study of the Effect of Immunoadsorption (IA) in Patients < 18 Years of Age with ME/CFS with Evidence of Autoantibodies (BIAKI)
Project status:
Ongoing
Country:
Germany
Principal investigator:
Wolfgang Ries
Organisations:
DIAKO Hospital
Research period:
2023-11-01
to 2025-11-30
Research types:
Clinical research
Research areas:
Immunological dysfunction
Repeat Immunoadsorption Post Covid ME/​CFS (RIA)
Project status:
Ongoing
Country:
Germany
Principal investigator:
Carmen Scheibenbogen
Organisations:
Charité – University Medicine Berlin
Research period:
2022-08-28
to 2025-01-30
Research types:
Clinical research
Research areas:
Immunological dysfunction
unCOVer Erlangen - ME/CFS
Project status:
Ongoing
Country:
Germany
Principal investigator:
Bettina Hohberger
Organisations:
University Clinic Erlangen
Research period:
Not available
Research types:
Clinical research
Research areas:
Immunological dysfunction